Spleen governs fluid-dampness transportation and transformation

and maintains normal production

transportation and distribution of human body fluid.Dysfunction of spleen in transporting fluid-dampness may lead to internal stagnation of excessive fluid and even production of fluid-dampness and phlegm-fluid retention

which may become blood stasis.Intermingled phlegm

dampness and blood stasis blockades blood and vessels and leads to coronary heart disease.The relationship between fluid-dampness and phlegm-fluid retention and the pathogenesis of coronary heart disease is analyzed generally from the aspect of fluid-dampness and phlegm-fluid and dyslipidemia

fibrinolytic dysfunction

as well as inflammatory reaction.Combined with the research results of genomics

proteomics and metabonomics of coronary heart disease syndrome of phlegm-turbidity

the authors explain that the pathogenesis of coronary heart disease is dysfunction of spleen in transportation

fluid-dampness and phlegm-fluid retention

which might provide theoretical support for Chinese medicine in treating coronary heart disease clinically from spleen.