Effect of Yiqi Jianpi Huaji Fang (益气健脾化积方) on Quality of Life in Gastric Cancer Patients with Chemotherapy of Qi Deficiency and Blood Stasis Type: A Double-blind Randomized Placebo-controlled Trial
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Effect of Yiqi Jianpi Huaji Fang (益气健脾化积方) on Quality of Life in Gastric Cancer Patients with Chemotherapy of Qi Deficiency and Blood Stasis Type: A Double-blind Randomized Placebo-controlled Trial
Journal of Traditional Chinese MedicineVol. 58, Issue 9, Pages: 759-762(2017)
CHEN Wanzhen, XU Tingting, ZHU Fangshi, et al. Effect of Yiqi Jianpi Huaji Fang (益气健脾化积方) on Quality of Life in Gastric Cancer Patients with Chemotherapy of Qi Deficiency and Blood Stasis Type: A Double-blind Randomized Placebo-controlled Trial[J]. Journal of Traditional Chinese Medicine2017, 58(9): 759-762.
CHEN Wanzhen, XU Tingting, ZHU Fangshi, et al. Effect of Yiqi Jianpi Huaji Fang (益气健脾化积方) on Quality of Life in Gastric Cancer Patients with Chemotherapy of Qi Deficiency and Blood Stasis Type: A Double-blind Randomized Placebo-controlled Trial[J]. Journal of Traditional Chinese Medicine2017, 58(9): 759-762.DOI: 10.13288/j.11-2166/r.2017.09.011.
Effect of Yiqi Jianpi Huaji Fang (益气健脾化积方) on Quality of Life in Gastric Cancer Patients with Chemotherapy of Qi Deficiency and Blood Stasis Type: A Double-blind Randomized Placebo-controlled Trial
Objective To evaluate the effect of Yiqi Jianpi Huaji Fang( 益气健脾化积方
YQJPHJF) on quality of life( QOL) of gastric cancer patients with chemotherapy of Qi deficiency and blood stasis type. Methods The researchers collected 58 gastric cancer patients with chemotherapy of Qi deficiency and blood stasis type from 7 hospitals to conduct a multi-centered
randomized
double-blind
single-dummy
paralleled
placebo-controlled trial. In addition to the chemotherapy of Docetaxel plus cisplatin
the treatment group( 31 cases) was administered oral YQJPHJF granules
the control group( 27 cases) was given YQJPHJF granules placebo
one dose daily for 8 weeks.The patients were followed before and in the treatment once a week to assess their QOL
Chinese medicine symptoms and signs and physical status. Results In the 8th week
the QOL score
classification and quantitation score and physical status score showed a significant statistic difference compared with those before treatment( P < 0. 05). In the control group
there was no significant statistic difference before and after treatment( P > 0. 05). In the 8th week
the classification and quantitation score of symptom and sign in Chinese medicine in the treatment group showed a significant statistic difference compared with that in the control group( P < 0. 05). Conclusion YQJPHJF could apparently improve the Chinese medicine symptoms and signs of gastric cancer with chemotherapy
and seems to have a potential efficacy in improving their QOL and physical status.
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