Autophagy is the process of cells degrading damaged organelles and biological macromolecules in lysosome to maintain cell stability under the influence of external environment. Autophagy participates in the development of many cardiovascular diseases. Atherosclerosis is the main cause of cardiovascular diseases. The pathogenic process is complex. The causes and pathogenesis are not clear yet. Based on spleen mitochondrial correlation theory

from the aspect of treating obstructive syndrome with tonifying methods and using invigorating herbs to remove obstruction

the authors discuss the relationship between atherosclerosis and autophagy. They hold that autophagy could make two-way intervention on atherosclerosis.