Pulmonary hypertension is one of the refractory complications of idiopathic pulmonary fibrosis（ IPS）.By the physiological and pathological features of five Zang organs in Chinese medicine

the location of IPF combined with pulmonary hypertension is in the lung

while the spleen

the kidney and the heart could be involved. The main pathogenesis is lung

spleen

kidney and heart Qi deficiency as well as heart and kidney Yang deficiency

and the latter one plays a more important role. Qi deficiency

blood stagnation

Yang deficiency

cold congealing

blood stasis

and water diffusion could all affect the movement of fluids and blood

while Qi deficiency and Yang deficiency both promote the generation of blood stasis

which is throughout the whole course of the disease. From the view of boosting Qi

warming Yang

invigorating blood and dissolving stasis

pulmonary hypertension could be effectively prevented or alleviated in IPF patients.