YAN Guangfu, HAN Dejun, LYU Shichao, et al. Literature Study on Chinese Medicine Treatment and Medication Rules for Elderly Hypertension,Middleaged and Young Hypertension Patients[J]. Journal of Traditional Chinese Medicine2017, 58(14): 1232-1236.
YAN Guangfu, HAN Dejun, LYU Shichao, et al. Literature Study on Chinese Medicine Treatment and Medication Rules for Elderly Hypertension,Middleaged and Young Hypertension Patients[J]. Journal of Traditional Chinese Medicine2017, 58(14): 1232-1236.DOI: 10.13288/j.11-2166/r.2017.14.016.
Literature Study on Chinese Medicine Treatment and Medication Rules for Elderly Hypertension,Middleaged and Young Hypertension Patients
Objective To explore the Chinese medicine treatment and medication rules for elderly hypertension and middle-aged and young hypertension patients
and to compare their similarities and differences. Methods Clinical studies about Chinese herbs treating elderly hypertension and middle-aged and young hypertension in CNKI
Wanfang data
and VIP database were collected. Information on treatment and herbs were extracted to build a prescription database. Frequency and cluster analysis were conducted. Results One hundred and sixty-one studies about elderly hypertension and forty studies about middle-aged and young hypertension were included. Sixteen therapeutic methods were involved
and among them
the top four most frequently used methods for elderly hypertension patients were invigorating blood( 77)
enriching and nourishing liver and kidney( 68)
calming liver and subduing Yang( 67)
and boosting Qi( 47). For middle-aged and young hypertension patients
the top four popular treatment were calming liver and subduing Yang( 21)
clearing liver heat and draining fire( 18)
invigorating blood( 15)
and dissolving phlegm and directing turbidity downward( 15). For the elderly hypertension
there were 195 correlated formulas with 181 herbs involved in; the top ten frequently used herbs were Niuxi [Achyranthes Bidentatae Radix
牛膝]
Fuling [Poria
茯苓]
Tianma [Gastrodiae Rhizoma
天麻]
Danshen [Salviae Miltiorrhizae Radix Et Rhizoma
丹参]
Danggui [Angelicae Sinensis Radix
当归]
Gouteng [Uncariae Ramulus Cum Uncis
钩藤]
Chuanxiong[Chuanxiong Rhizoma
川芎]
Huangqi [Astragali Radix
黄芪]
Zexie [Alismatis Rhizoma
泽泻] and Gancao[Glycyrrhizae Radix Et Rhizoma
甘草]. As for middle-aged and young hypertension
there were 53 correlated formulas with 115 herbs
and the top ten herbs were Gouteng
Fuling
Baishao [Paeoniae Radix Alba
白芍]
Tianma
Baizhu [Atractylodis Macrocephalae Rhizoma
白术]
Huangqin [Scutellariae Radix
黄芩]
Juhua [Chrysanthemi Flos
菊花]
Niuxi
Shijueming [Haliotidis Concha
石决明]and Zexie. The cluster analysis showed that there were five core herb clusters for treating elderly hypertension
and seven for middle-aged and young hypertension. Conclusion Both treatments for elderly hypertension and for middle-aged and young hypertension focus on calming liver and subduing Yang and invigorating blood
while the former one emphasizes boosting Qi and nourishing blood as well as enriching and nourishing liver and kidney
and draining dampness and dissolving phlegm as well as clearing liver heat and draining fire are also used; the latter one emphasizes clearing heat and draining fire as well as dissolving phlegm and directing turbidity downward
and enriching Yin and subduing Yang as well as soothing liver and regulating spleen are also used.
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Related Author
GAO Mengqi
WANG Anlu
XU Hao
ZHAO Lin
DING Shuchen
XUE Mei
XU Hao
LYU Xiaotong
Related Institution
Suzhou Hospital of Xiyuan Hospital,China Academy of Chinese Medical Sciences
Xiyuan Hospital,China Academy of Chinese Medical Sciences
Postdoctoral Research Station,China Academy of Chinese Medical Sciences
National Clinical Research Center for Chinese Medicine Cardiology,Xiyuan Hospital,China Academy of Chinese Medical Sciences
Graduate School,Beijing University of Chinese Medicine