Objective To explore the medication rule of antitumor herbs in Tujia medicine by analyzing the relevant papers. Methods According to Tujia Herb Records（ 土家族药物志）

a Tujia list of antitumor herbs was made. The keywords were selected from the list and used in literature search in China National Knowledge Infrastructure

Wan Fang Data

and Pub Med. Papers on commonly used herbs which had definite antitumor effect in Tujia medicine were collected to build a database for data analysis. Results There were 144 herbs with direct antitumor effect in Tujia medicine（ including 136 botanical drugs and 8 animal derived drugs）. With the highest frequency（ 11times） of appearing in the collected papers

the compositaes was most common in family and genera distribution

covering 7. 6% of antitumor herbs in Tujia medicine. In herb flavor distribution

bitter herbs were most common

covering 41. 7% of all herbs. There are 77 cool-natured herbs and 104 non-toxic herbs totally. Conclusion Most herbs for treating tumors in Tujia medicine are those with effects of clearing heat

attacking pathogen and resolving hard mass

and those without toxicity.