Objective To examine the effect and safety of Fulyuning Keli（ 复律宁颗粒） in treating heart failure complicated with arrhythmia of both Qi and Yin deficiency type. Methods Eighty heart failure complicated with arrhythmia patients of both Qi and Yin deficiency type were divided into treatment group and control group

40 cases in each group. The control group was given western medicine standardized treatment of heart failure complicated with arrhythmia. In addition to the standardized treatment

the treatment group was given Fulyuning Keli. Both groups were treated for 4 weeks. Patients’ cardiac functional grading

cardiac ultrasound indexes including ejection fraction（ EF）

stroke volume（ SV） and left ventricular end diastolic dimension（ LVEDD）

brain natriuretic peptide（ BNP）

6-min walking test

Chinese medicine syndrome score

as well as the scores of Minnesota life quality of heart failure questionnaire（ MLHFQ）

Hamilton anxiety scale（ HAMA） and Hamilton depression scale（ HAMD） before and after treatment were compared. Heart function efficacy and arrhythmia efficacy in both groups were evaluated.Results After treatment

changes of heart function effect（ total effective rate 80. 00% in the treatment group

55. 00% in the control group） and arrhythmia effect（ total effective rate 70. 00% in the treatment group

42. 50% in the control group） was significantly different（ P < 0. 05 or P < 0. 01）. After treatment

Chinese medicine syndrome score

6-min walking distance

as well as the scores of MLHFQ

HAMA and HAMD in both groups improved

and the treatment group was superior to the control group（ P < 0. 01）. BNP level in both groups decreased after treatment（ P < 0. 01）. The difference between both groups was not significant（ P > 0. 05）. The difference of cardiac ultrasound indexes in both groups before and after treatment was not significant（ P > 0. 05）. Conclusion In treating heart failure complicated with arrhythmia patients of both Qi and Yin deficiency type

Fulyuning Keli might improve heart function

reduce patients’ premature attack and improve patients’ clinical symptoms and life quality.