BI Yingfei, WANG Xianliang, ZHAO Zhiqiang, et al. Clinical Epidemiological Investigation on Current Syndrome Characteristics of Coronary Heart Disease in Chinese Medicine[J]. Journal of Traditional Chinese Medicine2017, 58(23): 2013-2019.
BI Yingfei, WANG Xianliang, ZHAO Zhiqiang, et al. Clinical Epidemiological Investigation on Current Syndrome Characteristics of Coronary Heart Disease in Chinese Medicine[J]. Journal of Traditional Chinese Medicine2017, 58(23): 2013-2019.DOI: 10.13288/j.11-2166/r.2017.23.009.
Clinical Epidemiological Investigation on Current Syndrome Characteristics of Coronary Heart Disease in Chinese Medicine
Objective To explore the Chinese medicine syndrome characteristics in patients with coronary heart disease in China. Methods Using clinical epidemiological survey method
the Chinese medicine syndrome characteristics in 8129 cases of coronary heart disease patients from 40 tertiary Chinese medicine hospitals or integrated Chinese and western medicine hospitals in 21 provinces
municipalities and autonomous regions in China were investigated by clinical cross-sectional survey. Results Chinese medicine syndromes of coronary heart disease mostly were the compound syndromes of deficiency in root cause and excess in manifestation and intermingled deficiency and excess. Deficiency of Qi( 67. 17%) was the main factor of deficiency in root cause. Blood stasis( 77. 89%) and phlegm-turbidity( 43. 97%) were the main factors of excess in manifestation. At the same time
the syndrome elements of Yin deficiency( 28. 97%)
Qi stagnation( 19. 60%) and Yang deficiency( 17. 39%) might also appear.Among them
Qi deficiency
blood stasis and phlegm-turbidity had the highest correlation degree. The most common syndromes were blood stasis due to Qi deficiency( 15. 06%)
phlegm and static blood due to Qi deficiency( 10. 95%)
blood stasis due to deficiency of both Qi and Yin( 9. 28%)
as well as intermingled phlegm and blood stasis( 8. 75%). The popularity of syndrome elements between male and female was basically the same. Blood stasis( 78. 81%/76. 19%)
phlegm-turbidity( 46. 79%/39. 00%) and heat amassment( 9. 70%/8. 27%) were more common in males than those in females. The females were more likely to suffer from Qi deficiency( 74. 74%/67. 01%)
Yin deficiency( 32. 21%/27. 08%)
Yang deficiency( 18. 45%/16. 73%) and blood deficiency( 12. 15%/8. 01%) than males. According to syndrome element popularity analysis in patients with coronary heart disease at different ages
the proportions of Qi deficiency( 54. 75%/60. 38%/69. 52%/73. 88%)
blood deficiency( 5. 57%/8. 63%/9. 40%/11. 86%)
Yin deficiency( 23. 93%/29. 27%/28. 69%/30. 08%)
Yang deficiency( 12. 13%/15. 01%/17. 33%/21. 93%) and fluid retention syndrome( 6. 23%/7. 21%/9. 53%/13. 24%) showed a significant growth trend with age( less than 45 years
45 to 60 years
61 to 75 years and older than 75 years).Conclusion At present
the Chinese medicine pathogenesis in patients with coronary heart disease might be " deficiency in root cause and excess in manifestation". The common syndromes are Qi deficiency( as root cause) and blood stasis and phlegm-turbidity( as manifestation).