Objective To evaluate the clinical efficacy of Jiawei Simiao Pills in treating acute gouty arthritis（AGA）. Methods Sixty patients with AGA were randomly divided into a western medicine group and a Chinese and western medicine group

with 30 cases in each group. The western medicine group was given Diclofenac Sodium Sustained Release Tablets orally

75 mg each time

once a day

and Sodium Bicarbonate Tablets

1000 mg each time

3 times a day orally. The Chinese and western medicine group was given Jiawei Simiao Pills in addition to the treatment same as in the western medicine group. The patients in the two groups were both treated for 3 days. During the treatment

if the joint pain got worse

patients switched to be treated with glucocorticoids after judgment. Before and after treatment

levels of white blood cells（WBC）

C reactive protein（CRP）

alanine aminotransferase（ALT）

aspartate aminotransferase（AST）

blood uric acid（UA）

and serum creatinine（Cr） were tested

and scores of joint pain

joint redness and swelling were evaluated respectively. The proportion of patients switching to glucocorticoids was compared between the two groups. Results There were 2 cases in the Chinese and western medicine group switching to glucocorticoids

significantly lower than 9 cases in the western medicine group（P < 0. 05）. After treatment

levels of WBC

CRP

and UA

as well as scores of joint pain and joint swelling in the Chinese and western medicine group were significantly lower than that before treatment（P < 0. 01）

and levels of CRP and UA

as well as scores of joint pain

joint redness and swelling were all lower than those in the western medicine group（P < 0. 05）.Conclusion Jiawei Simiao Pills could inhibit inflammatory reaction

relieve joint swelling and pain symptoms

and reduce the use of glucocorticoids in the treatment of AGA.