This article summarizes the physiological and pathological relationship between spleen and muscle.Based on the analysis of ancient and modern research literature about "spleen governing muscle"

this article explores its clinical manifestations in six aspects

including: 1) to treat Wei（ atrophy

痿）

selecting the Yangming channel only; 2) prolapse of the uterus is due to the spleen and muscle; 3) eyelids are ascribed to the spleen and blepharoptosis should be treated from the spleen; 4) obesity is always due to phlegm and dampness

which should be treated from fortifying the spleen to transmit dampness; 5) muscle Bi is always treated from the spleen; 6) Gan syndrome（ infantile malnutrition

疳） is always due to deficient muscle and spleen disorder

which provides a theoretical basis for clinical treatment.