A Randomize-Controlled Clinical Study on Acupuncture as Adjunctive Treatment for EV71 Type Severe Hand-Foot-Mouth Disease Complicated with Dysphagia

YANG Ying; LUO Jing; CUI Yajie

doi:10.13288/j.11-2166/r.2018.02.010

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A Randomize-Controlled Clinical Study on Acupuncture as Adjunctive Treatment for EV71 Type Severe Hand-Foot-Mouth Disease Complicated with Dysphagia

更新时间：2021-11-10

- A Randomize-Controlled Clinical Study on Acupuncture as Adjunctive Treatment for EV71 Type Severe Hand-Foot-Mouth Disease Complicated with Dysphagia
- Journal of Traditional Chinese Medicine Vol. 59, Issue 2, Pages: 128-131(2018)
- 作者机构：
  
  郑州儿童医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2018.02.010
  CLC： R246.4
- Published：2018
- 稿件说明：
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[1]杨颖,罗静,崔亚杰.针刺辅助治疗EV71型重症手足口病合并吞咽困难随机对照临床研究[J].中医杂志,2018,59(02):128-131.

YANG Ying, LUO Jing, CUI Yajie. A Randomize-Controlled Clinical Study on Acupuncture as Adjunctive Treatment for EV71 Type Severe Hand-Foot-Mouth Disease Complicated with Dysphagia[J]. Journal of Traditional Chinese Medicine2018, 59(2): 128-131.
[1]杨颖,罗静,崔亚杰.针刺辅助治疗EV71型重症手足口病合并吞咽困难随机对照临床研究[J].中医杂志,2018,59(02):128-131. DOI： 10.13288/j.11-2166/r.2018.02.010.

YANG Ying, LUO Jing, CUI Yajie. A Randomize-Controlled Clinical Study on Acupuncture as Adjunctive Treatment for EV71 Type Severe Hand-Foot-Mouth Disease Complicated with Dysphagia[J]. Journal of Traditional Chinese Medicine2018, 59(2): 128-131. DOI： 10.13288/j.11-2166/r.2018.02.010.

摘要

目的观察针刺辅助治疗EV71型重症手足口病合并吞咽困难的临床疗效及安全性。方法将66例EV71型重症手足口病合并吞咽困难患儿随机分为干预组和对照组各33例。两组均予西药常规治疗

干预组在常规治疗基础上给予针刺治疗

对照组采用与干预组相同的穴位上给予不入皮的医用胶布固定亳针的安慰针方法。两组均每周针刺5次

治疗10

0次。治疗前后进行床旁吞咽功能评估量表（BSA）评分

治疗后记录24h吸痰次数和吸痰间隔时间

并评价安全性和临床疗效。结果干预组治愈率为70.97%

总有效率为90.32%

优于对照组的39.39%和69.69%（P

0.05）。两组治疗后BSA评分均下降

且干预组较对照组降低更明显（P

0.05）。治疗后干预组24 h吸痰次数少于对照组

吸痰间隔时间长于对照组（P

0.05）。干预组出现2例轻度不良事件

表现为针刺部位红肿和青紫。结论针刺辅助治疗EV71型重症手足口病可提高临床疗效

能明显改善患儿吞咽困难症状

安全性较好。

Abstract

Objective To examine the clinical effect of acupuncture in treating EV71 type severe hand-footmouth disease（ HFMD） complicated with dysphagia. Methods Sixty-six EV71 type severe HFMD complicated with dysphagia children patients were randomized into intervention group and control group

33 cases in each group.Both groups were given western medicine routine treatment. The intervention group was added acupuncture. The control group was given placebo needling（ medical tape fixed filiform needle without penetrating the skin） on the same points as the test group. Treatment was given five times a week totally for eight weeks. Bedside swallowing assessment（ BSA） scoring was made before and after treatment. After treatment

24-hour sputum suction times and the interval time of sputum suction were recorded. Safety and clinical effect was evaluated. Results The cure rate in the intervention group was 70. 97%; the total effective rate was 90. 32%

which was superior to 39. 39% and 69. 69% in the control group（ P < 0. 05）. After treatment

BSA scores in both groups decreased and the intervention group was lower than the control group（ P < 0. 05）. After treatment

24-hour sputum suction times in the intervention group was less than that in the control group; the interval time of sputum suction was longer than that in the control group（ P <0. 05）. Swelling and bruise in acupuncture points occurred in two cases in the intervention group. Conclusion Acupuncture intervention might improve the clinical effect in treating EV71 type severe HFMD and improve symptoms of dysphagia in children patients.

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Related Institution

School of Acupuncture-Moxibustion and Tuina，Beijing University of Chinese Medicine

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Third Affiliated Hospital of Beijing University of Chinese Medicine

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Nanjing University of Chinese Medicine

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