Mechanism of Dredging Intestines to Dispel Heat Method in Treating Stroke Based on Brain-intestine Interaction

LI Jianxiang; GUO Weifeng; FU Shuping; YUAN Mengguo; LIU Yunfang; GU Heng

doi:10.13288/j.11-2166/r.2018.04.006

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Mechanism of Dredging Intestines to Dispel Heat Method in Treating Stroke Based on Brain-intestine Interaction

更新时间：2021-11-10

- Mechanism of Dredging Intestines to Dispel Heat Method in Treating Stroke Based on Brain-intestine Interaction
- Journal of Traditional Chinese Medicine Vol. 59, Issue 4, Pages: 292-294(2018)
- 作者机构：
  
  1. 南京中医药大学第三附属医院
  2. 南京中医药大学
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2018.04.006
  CLC： R255.2
- Published：2018
- 稿件说明：
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[1]李建香,过伟峰,傅淑平,袁梦果,刘云芳,顾恒.基于脑肠互动探讨通腑泻热法治疗中风的机制[J].中医杂志,2018,59(04):292-294+298.

LI Jianxiang, GUO Weifeng, FU Shuping, et al. Mechanism of Dredging Intestines to Dispel Heat Method in Treating Stroke Based on Brain-intestine Interaction[J]. Journal of Traditional Chinese Medicine2018, 59(4): 292-294.
[1]李建香,过伟峰,傅淑平,袁梦果,刘云芳,顾恒.基于脑肠互动探讨通腑泻热法治疗中风的机制[J].中医杂志,2018,59(04):292-294+298. DOI： 10.13288/j.11-2166/r.2018.04.006.

LI Jianxiang, GUO Weifeng, FU Shuping, et al. Mechanism of Dredging Intestines to Dispel Heat Method in Treating Stroke Based on Brain-intestine Interaction[J]. Journal of Traditional Chinese Medicine2018, 59(4): 292-294. DOI： 10.13288/j.11-2166/r.2018.04.006.

摘要

通腑泻热是治疗中风的重要法则

但其治疗机制仍未明确。结合近期脑肠相关研究结果

从脑肠互动、脑-肠轴、脑肠肽、肠道菌群角度对通腑泻热法治疗中风的机制进行探讨。提出脑-肠轴为阐明通腑泻热法治疗中风的机制奠定了基础

脑肠肽是研究通腑泻热法治疗中风的物质基础

而肠道菌群则是治疗的重要靶点。认为机体通过脑-肠轴调节脑肠功能

形成脑肠互动

脑肠肽、肠道菌群在其中发挥重要作用

可为脑肠相关疾病的防治研究提供新思路。

Abstract

Dredging intestines to dispel heat is an important principle in treating stroke

while the therapeutic mechanism is not clear. Combined with recent research results related with brain and intestine

the authors explore the mechanism of dredging intestines to dispel heat method in treating stroke from the aspects of brain-intestine interaction

brain-intestine axis

and braingut petide and intestinal flora. The authors put forward that brain-intestine axis lays the foundation for explaining the mechanism of dredging intestines to dispel heat method in treating stroke. Braingut petide is the material basis in researching dredging intestines to dispel heat method in treating stroke

while intestinal flora is the important target of therapy. The authors hold that body regulates brain-intestine function by brain-intestine axis and brain-intestine interaction. In this process

braingut petide and intestinal flora play an important role

which may provide new idea for researches of prevention and treatment of brain-intestine related diseases.

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