Objective To retrospectively analyze clinical curative effect of Qinghuang Powder Capsule as the main method in treating patients with myelodysplastic syndrome. Methods One hundred and fifty cases of myelodysplastic syndrome were collected. All patients have used Qinghuang Powder Capsule for at least 24 months（ 0. 3 g daily

taken after dinner）

at the same time combining with orally taking androgen and decoction for tonifying kidney and spleen. Peripheral blood hemoglobin（ HGB）

platelet count（ PLT）

and neutrophil count（ ANC） of patients after being treated for 3

6

9

16

24

30 and 40 months were observed. The case number and time of each index acquiring hematology progress were evaluated. The time it took for each index of patients with different risk factors and bone marrow hyperplasia degree to acquire hematology progress were compared; and the improvement of anemia and erythrocyte infusion condition in the 40 th month of treatment was recorded. Results There were 150 patients who completed the 24-month treatment

of which 136 completing 30-month treatment

and 118 completing 40-month treatment. In 150 cases

the number of patients whose HGB

PLT and ANC before treatment lower than normal was 115

129 and 56 cases respectively. During 40-month treatment

hematology progress rate of patients with abnormal HGB were higher and hematology progress time was shorter than those with abnormal PLT and ANC（ P < 0. 05）

while the difference between patients with abnormal PLT and ANC was not statistically significant（ P > 0. 05）. There was no significant difference in time took for each index improvementbetween patients with different risk to acquire hematological progress（ P > 0. 05）. The time took for PLT improvement of patients with low proliferative to acquire hematological progress was significantly longer than that of non-hypoproliferative patients（ P < 0. 05）. Through Person correlation test

the patients with erythrocyte infusion dependence were significantly reduced as treatment time stretched（ r =-0. 92

P < 0. 05）. Conclusion Qinghuang Powder Capsule as the main method treating myelodysplastic syndrome could obviously improve HGB

PLT

ANC in peripheral blood

and improved HGB more significantly. Its onset time was short and could work for a long time.