Objective To analyze the syndrome differentiation rule in treating patients with coronary heart disease（CHD） angina pectoris collateral-qi deficiency and stagnation syndrome under the guidance of vessel-collateral theory and yingfen-weifen theory by data mining method. Methods Around a variety of elements

such as CHD angina pectoris disease

syndrome

symptom

method

recipe and medicine

comprehensive data analysis methods

including Bayesian network

frequency analysis

cluster analysis

descriptive analysis and Pearson correlation analysis

were applied to objectively reveal the clinical syndrome differentiation rule in treating CHD angina pectoris collateral-qi deficiency and stagnation syndrome under the guidance of vessel-collateral theory. Results The symptoms extracted by Bayesian network

which had a strong causal relationship with collateral-qi deficiency and stagnation syndrome were cardiothoracic dull pain

dispiritedness and weakness

deep and thready pulse

palpitation and disinclination to talk

as well as tongue with teeth prints. Frequency analysis method was used to analyze the symptoms and herbs of collateral-qi deficiency and stagnation syndrome. The result showed that symptoms with high frequency were cardiothoracic dull pain

oppression in chest and panting

7. 41% and 6. 79%. Herbs with high frequency were Xiyangshen（Radix Panacis Quinquefolii

西 洋参

5. 83%） and Chishao（Radix Paeoniae Rubra

赤 芍

5. 59%）.Herb cluster analysis showed meaningful clustering combinations

such as Fried Suanzaoren（Semen Ziziphi Spinosae

酸枣仁）-Hehuanhua（Flos Albiziae

合欢花）

Maidong（Radix Ophiopogonis

麦冬）-Wuweizi（Fructus Schisandrae Chinensis

五味子） and Fuling（Poria

茯苓）-Zexie（Rhizoma Alismatis

泽泻）. Herb proportion of commonly used herb pair was summarized by descriptive analysis; the commonly used proportion of Xiyangshen-Shenghuangqi（Radix Astragali seu Hedysari

生 黄芪） was 12 g ∶ 30 g. Pearson correlation analysis showed correlation strength between high frequency herb pairs and syndrome and the correlation degree of all combinations was more than0. 4. Conclusion By data mining in treating CHD angina pectoris cases

the authors further explained the recipemedicine rule in patients with CHD angina pectoris collateral-qi deficiency and stagnation syndrome under the guidance of vessel-collateral theory and the therapeutic principle of "taking unblocked transmission as normal functional state of collateral".