Objective To examine the clinical effect of Jinbi Dihuang Decoction（金萆地黄汤） in treating male infertility combined with teratospermia. Methods One hundred patients with male infertility and teratospermia were treated by Jinbi Dihuang Decoction

ONE dose every day

for 12 weeks. The changes of patients’ teratozoospermia index

sperm deformity index

normal morphology sperm rate

normal sperm count and normal forward motile sperm count were examined before and after treatment. The clinical effect and the normal morphology sperm rates in patients with different level of teratospermia were evaluated. Results Eighty-one patients completed the research. After treating for 12 weeks

34 patients（42. 0%） attained clinical recovery; 26 patients（32. 1%） seemed effective

with31 patients（38. 3%） ineffective. After treatment

normal morphology sperm rate increased; teratozospermia index and sperm deformity index decreased（P < 0. 01）. Compared before treatment

normal sperm count and normal forward motile sperm count increased after treatment（P < 0. 05）. After treatment

there was significant difference in the normal morphology sperm rates of patients with different level of teratospermia

with more normal sperms in the mild teratospermia increased（P < 0. 05）. No side effect was found in patients during the treatment. Conclusion Jinbi Dihuang Decoction might improve male infertility combined with teratospermia patients’ teratospermia and multiple sperm defects indexes. Moreover

the milder the level of sperm deformity

the effect better.