The standardized implementation of clinical research is an important guarantee to evaluate the effectiveness of the study protocol. This article is to summarize the organization structure and research process of international clinical trial implementation. Taking impact of acupuncture combined with clomiphene on polycystic ovarian syndrome anovulation women’ s live birth: international cooperative randomized controlled trial（ PCOSAct） for example

this article introduces exploration and innovation of standardization implementation in department of gynaecology in First Hospital Affiliated to Heilongjiang University of Chinese Medicine in the process of clinical research of Chinese medicine

by adopting internationalized organizational management model

emphasizing the implementation preparation

emphasizing ethics retrial and registration update

regular meeting of steering committee

as well as adopting the methods of site inspection and international joint inspection

to provide reference for Chinese medicine clinical research internationalization.