Objective To analyze the clinical effect of invigorating spleen and benefiting Qi method for reducing patients’ digestive tract reaction in chemotherapy regimen with cisplatin. Methods Literature conforming to the inclusion criteria was reviewed in Pubmed

Embase

Cochrane Library

Sino Med

China National Knowledge Infrastructure

Wan Fang Data and VIP Data

from the beginning of the database to April 25 th

2017. The papers were included in Meta analysis after the quality was evaluated by Jadad scale. Results Totally

24 papers of randomized controlled trials were included

with 848 patients in the Chinese and western medicine combination group and 816 patients in the simple chemotherapy group. The quality of included papers was 1-3 score. Meta analysis results showed that the Chinese and western medicine combination group was superior to the simple chemotherapy group at the aspects of nausea-vomitting [RR = 0. 71

95% CI（ 0. 64-0. 78）

P < 0. 001]

anorexia [RR = 0. 51

95% CI（ 0. 34-0. 76）

P < 0. 001]

abnormal defecation [RR = 0. 62

95% CI（ 0. 45-0. 86）

P = 0. 004]

tumor curative effect index [RR = 1. 14

95% CI（ 1. 07-1. 21）

P < 0. 001] and life quality [RR = 1. 59

95% CI（ 1. 38-1. 83）

P < 0. 001]. Conclusion Invigorating spleen and benefiting Qi herbs might reduce chemotherapy patients’ incidence of nausea-vomitting

anorexia and abnormal defecation. Moreover

the herbs might improve chemotherapy effect and quality of life.