This paper put forward the essence of pathological evolution of atherosclerosis is the process of blood vessels from homeostasis to dyshomeostasis. Its occurrence is a systematic change jointly involving dynamic

longterm

and blood-vessel-heart-spirit functional abnormality. This paper took the homeostasis of vessel as the entry point

the development track of plaque forming-vulnerability-rupture as elaboration carrier

combined with the primary and secondary

degree of urgency of blood

vessel

heart and spirit associated diseases in each stage

ultimately summarized the treatment rules of three stages of atherosclerosis based on disease-syndrome-time

which was early stage of vascular dyshomeostasis-plaque formation

characterized by blood-vessel function imbalance. The disease was in blood and vessel

and should be treated by tonifying the kidney and fortifying the spleen

resolving phlegm and dissipating masses

and regulating and harmonizing qi and blood; medium stage of vascular dyshomeostasis-plaque vulnerable

characterized by vascular structure imbalance. The disease was located in vessel and spirit

and should be treated by nourishing yin and detoxifying

regulating and harmonizing ying and wei

unblocking vessels and regulating spirit; late stage of vascular dyshomeostasis-plaque disruption

characterized by vascular structure damage. The disease was located in blood and heart

and should be treated in regulating qi and activating blood

tonifying qi and safeguarding the heart.