The location of defandrative cheilitis is the lip

which is usually related to the spleen and stomach

and sometime involved with heart

liver and kidney. The basic pathogenesis is the accumulating heat attacking lips caused by spleen deficiency while stomach fire excess. Treatment should be based on tonifying spleen and eliminating stagnation

clearing heat and detoxification

nourishing blood and moistening lips. Internal treatment needs to distinguish the deficiency and excess. Modified Zhizhu Xiaoji Pills（ 枳术消积丸） should be used in patients with heat accumulation and stomach fire excess to eliminate food stagnation and clear stomach heat and fire. Modified Shiquan Shimei Decoction（ 十全十美汤） is used to replenish qi and tonify spleen

nourish blood and moisten dryness for patients with spleen deficiency and blood dryness. Modified Xiaoji Yangxin Decoction（ 消积养阴汤） should be used for patients with coexistence of deficiency and excess to tonify spleen and eliminate stagnation

clear heat and nourish yin.