Through the concept and method of information medicine

a complete knowledge system can be formed by physiology

pathology and diagnosis-treatment of traditional Chinese medicine（ TCM）. In physiology of TCM

there are three core concepts

including zang-fu viscera

channel and qi and blood. They are nonlinearly related to each other and form a life information network

whose three major mechanisms are qi transformation

conveyance and dispersion. In pathology of TCM

human will be in a healthy state if all physiological mechanisms are functioning normally and the body is balanced. Otherwise

the lesions such as deficiency

stasis and toxicity will be occurred

which can result in the imbalance of body and the generation of disease. In diagnosis-treatment of TCM

methods of syndrome differentiation such as syndrome differentiation of eight principles

syndrome differentiation of qi-blood-body fluid

syndrome differentiation of zang-fu viscera

syndrome differentiation of channel theory

syndrome differentiation of sanjiao theory and syndrome differentiation of weifen are applied to determine the state of the body hierarchically and provide a basis for selecting the treatment decision. The basic two treatment methods are tonifying and purging

and the direct order parameters are yin-yang（ qi-blood）

which play a mediating role to tonify deficiency

dispel stasis and detoxify through coordination.