Treatment of desire and bitterness in five-visceral with tonifying and dispersing methods for good prognosis theory currently has two versions of the Inner Canon of Yellow Emperor（《黄帝内经》） and Auxiliary Verses of Crucial Elements of Medication in Zang-Fu（《辅行诀脏腑用药法要》） which simplified as Auxiliary Verses（《辅行诀》）.There are many similarities between the two books in terms of text content

but there are many differences in their connotations. In Inner Canon of Yellow Emperor

"the desire of five-visceral"means to the adaption to the physiological characteristics of five-visceral and "the bitterness of five-visceral"means the contrary to the physiological characteristics of the five internal organs. Five-flavors which can adapt to the physiological characteristics of five-visceral are used to tonify

and which are on the contrary side are used for dispersing. Auxiliary Verses puts forward the relationship between five-flavors and five-elements

which is different from Inner Canon of Yellow Emperor

that is

pungent corresponds to wood

salt corresponds to fire

sweet corresponds to soil

acid corresponds to gold

and bitter corresponds to water. And there are some principles in the choice of herbs of the formula. Firstly

use the flavor corresponding to the targeted zang-organ to tonify the deficiency. Secondly

use the flavor corresponding to the zang-organ which is superior to the targeted zang-organ to disperse its excess. Lastly

use the flavor corresponding to the zangorgan which is inferior to the targeted zang-organ to disperse the bitterness. These two theories are analyzed and compared by exemplifying related prescriptions to provide a certain basis for clinically reasonable drug delivery.