Based on the traditional theory and the changes of modern lifestyle as well as the characteristics of the disease

this paper proposed that the pathogenesis of diabetes is"dysfunction of spleen transforming essences"developing to"turbidity accumulated into toxin"and then to"internal retention of turbidity and toxin". Through a more systematic and in-depth basic research and clinical observation

the pathological and utility mechanisms are explained from multiple levels and multiple perspectives. This paper believed that the dysfunction of spleen transforming essences is the pathological basis for the formation of diabetes

and turbidity is its main pathological product

dysfunction of spleen transforming essences is related to lipid metabolism disorders

and the generation of turbidity is associated with insulin dysfunction. "Turbidity accumulated into toxin"and the living environment and lifestyles are closely related

which results in internal retention of turbidity and toxin that erodes the viscera and meridians. Based on this core pathogenesis

the treatment of "clearing turbidity and detoxification"therapy was proposed

and its intervention effects were discussed from the perspectives of diabetic sugar and lipid toxicity.