ZHONG Haizhen, YAO Gang, YU Wenjuan, et al. Preliminary Screening of Forecast Indicators of Deficiency and Excess Syndrome in Patients with Asymptomatic Nephrogenic Hematuria[J]. Journal of Traditional Chinese Medicine2018, 59(24): 2111-2116.
ZHONG Haizhen, YAO Gang, YU Wenjuan, et al. Preliminary Screening of Forecast Indicators of Deficiency and Excess Syndrome in Patients with Asymptomatic Nephrogenic Hematuria[J]. Journal of Traditional Chinese Medicine2018, 59(24): 2111-2116.DOI: 10.13288/j.11-2166/r.2018.24.010.
Preliminary Screening of Forecast Indicators of Deficiency and Excess Syndrome in Patients with Asymptomatic Nephrogenic Hematuria
其中Hb和LDL-C在独立预测无症状肾源性血尿实证时具有统计学意义(P <0. 05)。结论 m Alb、GLO可作为无症状肾源性血尿虚证诊断的独立预测指标
Hb和LDL-C可作为无症状肾源性血尿实证诊断的独立预测指标。
Abstract
Objective To preliminarily screen out the forecast indicators of deficiency and excess of syndrome in patients with asymptomatic nephrogenic hematuria. Methods Clinical data of 257 patients with asymptomatic nephrogenic hematuria
including age
gender
course of disease
comorbidities
blood pressure
urinary occult blood
urine protein
urine sediment
urinary microalbumin(m Alb)
glycated hemoglobin
24-hour urine protein quantitative
globulin(GLO)
blood glucose
urea
creatinine
cystatin C
albumin
cholesterol
triglycerides
uric acid
high-density lipoprotein cholesterol(HDL-C)
low-density lipoprotein cholesterol(LDL-C)
hemoglobin(Hb)
hypersensitive C-reactive protein
erythrocyte sedimentation rate
complement C3
complement C4
IgA
IgG
IgM
whole blood viscosity
plasma viscosity and other indicators were collected. At the same time
by two doctors with senior titles
patients were divided into two groups according to the results of syndrome differentiation: the deficiency group and the non-deficiency group
the excess group and the non-excess group. The differences of the indicators among the deficiency group and the non-deficiency group
the excess group and the non-excess group were compared. Binary logistic regression was used to obtain indicators with independent predictive significance for the diagnosis of deficiency syndrome and excess syndrome. Results Among the 257 patients
there were 157 cases in the deficiency group and 100 cases in the non-deficiency group. Compared with patients with non-deficiency syndrome
there were statistically significant differences in gender
disease duration
systolic blood pressure
m Alb < 20 mg/L
urinary sediment from 50
000/mL to 500
000/mL
glycosylated hemoglobin
GLO
triglyceride
uric acid
HDL-C
Hb and IgG of patients with deficiency syndrome(P < 0. 05)
and m Alb and GLO were statistically significant for independently predicting asymptomatic nephrogenic hematuria(P < 0. 05). There were 32 cases in excess group
and225 cases in non-excess group. Compared with the non-excess group
the differences in gender
Hb
and LDL-C of excess group were statistically significant(P < 0. 05 or P < 0. 01)
and Hb and LDL-C were statistically significant in predicting asymptomatic nephrogenic hematuria with excess syndrome(P < 0. 05). Conclusion m Alb and GLO can be used as independent predictors for the diagnosis of asymptomatic nephrogenic hematuria. Hb and LDL-C can be used as independent predictors for the diagnosis of asymptomatic nephrogenic hematuria.