Analysis of Association Rules between Traditional Chinese Medicine Syndrome Factors,Risk Factors and Left Ventricular Remodeling in Patients with Coronary Heart Disease and Left Ventricular Remodeling

YAO Minglong; LIN Kan; ZHENG Guanyi; XIONG Shangquan; FU Kailong; LIU Wenhong

doi:10.13288/j.11-2166/r.2019.04.011

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Analysis of Association Rules between Traditional Chinese Medicine Syndrome Factors,Risk Factors and Left Ventricular Remodeling in Patients with Coronary Heart Disease and Left Ventricular Remodeling

更新时间：2021-11-10

- Analysis of Association Rules between Traditional Chinese Medicine Syndrome Factors,Risk Factors and Left Ventricular Remodeling in Patients with Coronary Heart Disease and Left Ventricular Remodeling
- Journal of Traditional Chinese Medicine Vol. 60, Issue 4, Pages: 311-316(2019)
- 作者机构：
  
  1. 福建医科大学附属协和医院
  2. 福建中医药大学附属人民医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2019.04.011
  CLC： R259
- Published：2019
- 稿件说明：
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[1]姚明龙,林侃,郑关毅,熊尚全,傅开龙,刘文洪.冠心病左室重构患者中医证素、危险因素与左室重构的关联规则分析[J].中医杂志,2019,60(04):311-316.

YAO Minglong, LIN Kan, ZHENG Guanyi, et al. Analysis of Association Rules between Traditional Chinese Medicine Syndrome Factors,Risk Factors and Left Ventricular Remodeling in Patients with Coronary Heart Disease and Left Ventricular Remodeling[J]. Journal of Traditional Chinese Medicine2019, 60(4): 311-316.
[1]姚明龙,林侃,郑关毅,熊尚全,傅开龙,刘文洪.冠心病左室重构患者中医证素、危险因素与左室重构的关联规则分析[J].中医杂志,2019,60(04):311-316. DOI： 10.13288/j.11-2166/r.2019.04.011.

YAO Minglong, LIN Kan, ZHENG Guanyi, et al. Analysis of Association Rules between Traditional Chinese Medicine Syndrome Factors,Risk Factors and Left Ventricular Remodeling in Patients with Coronary Heart Disease and Left Ventricular Remodeling[J]. Journal of Traditional Chinese Medicine2019, 60(4): 311-316. DOI： 10.13288/j.11-2166/r.2019.04.011.

摘要

目的探讨冠心病左室重构与证素、危险因素的关系。方法运用临床流行病学调查方法

对261例疑似冠心病患者进行冠状动脉造影和心脏彩超检查

对确诊为冠心病左室重构患者的中医证素和危险因素进行横断面调查

运用频数分析和关联规则方法进行数据统计。结果 261例疑似患者最终确诊为冠心病左室重构病例为231例。231例患者中病位证素以心（226例）、肺（116例）、肾（69例）为主;病性证素以血瘀（221例）、气虚（77例）、阴虚（72例）、阳虚（58例）为主。关联规则提示冠心病左室重构与心、肺、肾、血瘀、气虚、阳虚、阴虚等证素有关

在吸烟、年龄、男性、心、血瘀条件下出现左心室重构概率为98. 49%;冠心病左室重构患者2个证素以心与阳虚、心与气虚等组合多见

3个证素以心与阳虚、肾

心与阳虚、肺等组合多见。4个证素以心与阳虚、肾、血瘀

心与阳虚、肺、血瘀等组合多见。结论冠心病左室重构患者多见本虚标实

病位多与心、肺、肾相关

气虚、阴虚、阳虚等虚证是发病之本

血瘀、痰是发病之标

危险因素是发作的重要因素。

Abstract

Objective To investigate the relationship between left ventricular remodeling and syndrome elements and risk factors. Methods Using clinical epidemiological investigation methods

261 patients with suspected coronary heart disease underwent coronary angiography and echocardiography

and cross-sectional survey was conducted for traditional Chinese medicine（ TCM） syndromes and risk factors in patients with left ventricular remodeling diagnosed as coronary heart disease. The frequency analysis and the association rule method were used for data statistics.Results Totally 231 cases were final diagnosed of left ventricular remodeling in 261 suspected patients. Among the231 patients

the main pathogenic factors were heart（ 226 cases）

lung（ 116 cases）

and kidney（ 69 cases）; the main pathogenic factors were blood stasis（ 221 cases）

qi deficiency（ 77 cases）

yin deficiency（ 72 cases）

and yang deficiency（ 58 cases）. The association rule suggested that left ventricular remodeling was related to heart

lung

kidney

blood stasis

qi deficiency

yang deficiency

yin deficiency. The probability of left ventricular remodeling was 98. 49% under smoking

age

male

heart

and blood stasis conditions. For two syndrome elements

the combination of heart and yang deficiency

heart and qi deficiency were more common in patients with left ventricular remodeling of coronary heart disease. For three syndrome elements

the combination of heart

yang deficiency and kidney

heart

yang deficiency and lung were more common. For four syndromes

the combination of the heart

yang deficiency

kidney and blood stasis

heart

yang deficiency

lung and blood stasis were more common. Conclusion Patients with left ventricular remodeling in coronary heart disease are more likely to have root deficiency and manifestation excess

and the disease location is mostly related to heart

lung and kidney. Deficiency of qi

yin deficiency and yang deficiency were the causes of the disease. Blood stasis and phlegm are the targets of the disease

and risk factors are important factors for the onset of the disease.

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