Change Rules of FibroScan Detection Value and Its Correlation with Traditional Chinese Medicine Syndrome Elements in 108 Patients with Hepatitis Cirrhosis
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Change Rules of FibroScan Detection Value and Its Correlation with Traditional Chinese Medicine Syndrome Elements in 108 Patients with Hepatitis Cirrhosis
Journal of Traditional Chinese MedicineVol. 60, Issue 5, Pages: 410-414(2019)
DOU Zhili, WU Xiuyan, WANG Tianfang, et al. Change Rules of FibroScan Detection Value and Its Correlation with Traditional Chinese Medicine Syndrome Elements in 108 Patients with Hepatitis Cirrhosis[J]. Journal of Traditional Chinese Medicine2019, 60(5): 410-414.
DOU Zhili, WU Xiuyan, WANG Tianfang, et al. Change Rules of FibroScan Detection Value and Its Correlation with Traditional Chinese Medicine Syndrome Elements in 108 Patients with Hepatitis Cirrhosis[J]. Journal of Traditional Chinese Medicine2019, 60(5): 410-414.DOI: 10.13288/j.11-2166/r.2019.05.012.
Change Rules of FibroScan Detection Value and Its Correlation with Traditional Chinese Medicine Syndrome Elements in 108 Patients with Hepatitis Cirrhosis
Objective To analyze the change rules of FibroScan detection value( FS value) of patients with hepatitis cirrhosis in different disease stages and levels
and its correlation with traditional Chinese medicine( TCM) disease syndrome elements. Methods A total of 108 patients with hepatitis cirrhosis were included
of which 69 were compensated and 39 were decompensated. The syndrome identification criteria were developed
and the disease syndrome elements of each patient were determined. The patient information was collected
and Child-Pugh scores on patients were performed. Then grade according to scores
and model for end-stage liver disease( MELD) scores were evaluated. FS value was detected. The FS values of patients with different stages and different Child-Pugh grades were compared
and the correlation between FS values and disease syndrome elements were analyzed. Results FS value in patients with compensated liver cirrhosis was significantly lower than that in patients with decompensation( P <0. 01). There was a positive correlation between FS value and Child-Pugh score
Child-Pugh grade as well as MELD score( P < 0. 01). The distribution of common syndrome elements in compensatory hepatitis cirrhosis patients was as follows: yin deficiency( 45 cases)
qi stagnation( 43 cases)
and yang deficiency( 39 cases). The distribution of common syndromes in patients with liver cirrhosis in decompensated stage was as follows: water retention( 34 cases)
yin deficiency( 30 cases)
and blood stasis( 29 cases). The distribution frequency of blood stasis
yang deficiency
qi deficiency and water retention was significantly different between the two groups( P < 0. 05). In the patients with liver cirrhosis at compensatory stage
the FS values of the patients with blood stasis
yin deficiency
damp-heat
yang deficiency and water retention were higher than those of non-appearance patients without above syndromes. The FS value of patients with qi stagnation was lower than that of patients without qi stagnation( P < 0. 05). In the decompensated patients
the FS value of patients with qi stagnation syndrome was lower than that of patients without qi stagnation. The FS values of patients with blood stasis
yin deficiency
damp-heat
qi deficiency
yang deficiency
and water retention were higher than those of patients without above syndromes. Among them
the comparison of whether or not blood stasis
water retention
and yang deficiency were statistically significant( P < 0. 05). Conclusion The FS detection value of patients with hepatitis and cirrhosis increase with the aggravation of the disease. There is a certain correlation between TCM syndrome elements and the FS detection value of the patients with liver cirrhosis. The patients with blood stasis
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