Objective To make a comprehensive summary of the clinical research statues of Baduanjin（ 八段锦）and to provide the evidence basis for the application of Baduanjin clinical healthcare. Methods We performed a search for Chinese and English studies in the following databases: Chinese National Knowledge Infrastructure

Wanfang Data

VIP database

Sino Med Pub Med

EMbase and Cochrane Library. The search strategy included terms relating to or describing Baduanjin. Studies published between the day since the database was established and December31

2017 were retrieved. The literature screening and data extraction was conducted strictly according to the criteria.SPSS 22. 0 software was used to analyze the basic information

subjects

sample size

Baduanjin exercises

outcomes

and research results. The method of quality evaluation was included in the randomized controlled trials using the Risk of bias（ ROB） tool in Rev Man 5. 3 software. Results A total of 552 papers were identified

including 33（ 6. 0%） systematic reviews

379（ 68. 6%） randomized controlled trials

46（ 8. 3%） quasi-randomized controlled trials

and 5（ 0. 9%） case-control trials

6（ 1. 1%） cohort studies

76（ 13. 8%） case series reports

and 7（ 1. 3%） study protocols. The top 10 diseases of the application with Baduanjin were diabetes

chronic obstructive pulmonary disease

hypertension

coronary heart disease

stroke

cervical spondylosis

hyperlipidemia

lumbar disc herniation

perimenopausal syndrome

and knee osteoarthritis. The most chosen standard of Baduanjin was the version compiled by the General Administration of Sport of China in 2003. Baduanjin was practiced 41 minutes at average

with a frequency of once or twice per day and at least 3 days a week

and the average treatment cours was 4 months.The vast majority of the studies（ 93. 6%

510/545） obtained positive results

with 4. 6%（ 25/545） did not clarify the effects of Baduanjin

and 1. 8%（ 10/545） of the studies were negative. Most of the studies had a small sample size

and the methodological quality of randomized controlled trials was relatively low. No serious adverse events related to Baduanjin were reported. Conclusion The quantity of clinical studies on Baduanjin is substantial. However

the differences of Baduanjin intervention among included studies were obvious

which needs further standardization and unification.