Objective To study the effects of traditional Chinese medicine（TCM） treatment on the lifetime and survival rate of elderly patients with advanced non-small cell lung cancer（NSCLC） after treated with cryoablation.Methods A total of 106 cases of elderly patients with advanced NSCLC who treated with cryoablation from January1

2012 to June 30

2017 were retrospectively collected. According to the post-operative treatment methods

they were divided into TCM treatment group

integrated TCM and western medicine group

and the western medicine treatment group. The primary observation indexes were survival times after operation

half-year survival rate and 1-year survival rate. Results Half-year and 1-year survival rate of the TCM treatment group was 68% and 42% respectively

which was higher than 44% and 25% in the western medicine treatment group. The survival time of the TCM treatment group was 15 months（95% CI: 7. 58-22. 42）

which was longer than 9 months（95% CI: 4. 60-13. 40） in the western medicine treatment group. The difference was statistically significant（P < 0. 05）. Comparison between the integrated TCM and western medicine group with the other 2 groups showed no statistically significant difference（P > 0. 05）. The half-year survival rate was 66% in patients who were treated with TCM

and the 1-year survival rate was 41%

which were higher than 44% and 25% in the patients without TCM treatment. The post-operative survival time was 15 months for patients treated with TCM（95% CI: 11. 35-18. 65）

which was longer than 9 months for patients without TCM treatment（95% CI: 4. 60-13. 40）. The difference was statistically significant（P < 0. 05）. Patients who received anti-tumor therapy with western medicine showed lower post-operative survival rate and shorter post-operative survival

but the difference was not statistically significant（P > 0. 05）. Conclusion TCM treatment is helpful for the prolongation of the survival time of advanced NSCLC patients after cryoablation.