Objective To analyze the traditional Chinese medicine（TCM） syndrome characteristics of heart failure with normal ejection fraction（HFNEF） patients and compare with the patients of heart failure with reduced ejection fraction（HFREF）. Methods A total of 60 patients with HFNEF and 60 patients with HFREF were selected as the HFNEF group and HFREF group. On-site questionnaire survey was used to collect demographic characteristics

disease-related information

the four diagnostic information of TCM

and the TCM syndrome elements to establish a database. The weight coefficient of TCM syndrome elements was analyzed by double percentage method.Results General epidemiological characteristics: the average age

proportion of female patients and proportion of patients with the history of hypertension or atrial fibrillation in HFNEF group were all higher than those in HFREF group. The proportion of smoking or drinking patients and those of patients with the history of coronary heart disease or old myocardial infarction or diabetes were all lower than those of HFREF group with significant difference（P <0. 05）. TCM syndrome elements distribution: qi deficiency

yin deficiency and yang deficiency were the main root deficiency syndrome elements in patients with HFNEF; blood stasis

phlegm turbidity

water retention

heat accumulation and yang hyperactivity. were the main manifestation excess syndrome elements. Comparison of the weight coefficient of TCM syndrome elements of both groups showed the weight coefficients of yin deficiency

phlegm turbidity

water retention

heat accumulation

fluid deficiency and yang hyperactivity in the HFNEF group（195. 87

149. 58

105. 45

71. 16

50. 00

21. 16） were respectively higher than those in the HFREF group（113. 68

133. 68

82. 62

45. 44

16. 03

9. 40）; the weight coefficients of qi deficiency

blood stasis

qi stagnation and yang deficiency（287. 85

254. 28

41. 67

22. 40） were respectively lower than those in the HFREF group（305. 56

269. 23

79. 77

61. 83）. Conclusion Deficiency in root and excess in manifestations are the main characteristics of TCM syndrome elements in either HFNEF group or HFREF group. Qi deficiency and blood stasis are the typical TCM syndrome characteristics of both groups. However

compared with HFREF

yin deficiency is more common in the root deficiency syndromes and the excess syndrome elements such as the phlegm turbidity

water retention and heat accumulation are more prominent in patients with HFNEF.