Clinical Observation on Treatment of 31 Cases of Angina Pectoris after Percutaneous Coronary Intervention with Traditional Chinese Medicine Syndrome Differentiation

HUANG Chuanhui; FAN Ruihong; LIU Hongbin

doi:10.13288/j.11-2166/r.2019.24.012

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Clinical Observation on Treatment of 31 Cases of Angina Pectoris after Percutaneous Coronary Intervention with Traditional Chinese Medicine Syndrome Differentiation

更新时间：2021-11-10

- Clinical Observation on Treatment of 31 Cases of Angina Pectoris after Percutaneous Coronary Intervention with Traditional Chinese Medicine Syndrome Differentiation
- Journal of Traditional Chinese Medicine Vol. 60, Issue 24, Pages: 2118-2122(2019)
- 作者机构：
  
  1. 天津市中医药研究院附属医院
  2. 天津市河西区天塔街社区卫生服务中心
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2019.24.012
  CLC： R259
- Published：2019
- 稿件说明：
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[1]黄传惠,樊瑞红,刘洪斌.中医辨证辅助治疗经皮冠状动脉介入术后心绞痛31例临床观察[J].中医杂志,2019,60(24):2118-2122.

HUANG Chuanhui, FAN Ruihong, LIU Hongbin. Clinical Observation on Treatment of 31 Cases of Angina Pectoris after Percutaneous Coronary Intervention with Traditional Chinese Medicine Syndrome Differentiation[J]. Journal of Traditional Chinese Medicine2019, 60(24): 2118-2122.
[1]黄传惠,樊瑞红,刘洪斌.中医辨证辅助治疗经皮冠状动脉介入术后心绞痛31例临床观察[J].中医杂志,2019,60(24):2118-2122. DOI： 10.13288/j.11-2166/r.2019.24.012.

HUANG Chuanhui, FAN Ruihong, LIU Hongbin. Clinical Observation on Treatment of 31 Cases of Angina Pectoris after Percutaneous Coronary Intervention with Traditional Chinese Medicine Syndrome Differentiation[J]. Journal of Traditional Chinese Medicine2019, 60(24): 2118-2122. DOI： 10.13288/j.11-2166/r.2019.24.012.

摘要

目的观察中医辨证辅助治疗经皮冠状动脉介入（PCI）术后心绞痛的临床疗效。方法 62例PCI术后心绞痛患者随机分为治疗组和对照组各31例。对照组给予常规治疗

治疗组在对照组基础上给予中医辨证治疗

均治疗4周。比较两组患者中医证候疗效、心绞痛疗效、心电图疗效;比较两组患者治疗前后硝酸甘油使用量、血脂[甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）

总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）]、超敏C反应蛋白（hs-CRP）及D-二聚体水平。结果两组患者中医证候疗效（治疗组总有效率为87.10%

对照组为58.06%）、心绞痛疗效（治疗组总有效率为80.65%

对照组为70.97%）、心电图疗效（治疗组总有效率为77.42%

对照组为67.74%）比较

治疗组均优于对照组（P<0.05）。治疗后两组患者硝酸甘油用量、TC、TG、LDL-C、D-二聚体、hs-CRP均较治疗前明显下降（P<0.05）

且治疗后治疗组低于对照组（P<0.05）;两组治疗后HDL-C均较治疗前明显升高（P<0.05）

且治疗组高于对照组（P<0.05）。结论中医辨证辅助治疗可显著改善PCI术后心绞痛患者中医证候、缓解心绞痛

并改善血脂水平、降低hs-CRP以及D-二聚体水平、减少硝酸甘油用量。

Abstract

Objective To investigate the clinical effect of traditional Chinese medicine（TCM） syndrome differentiation in the treatment of angina pectoris after percutaneous coronary intervention（PCI）. Methods A total of 62 patients with angina pectoris after PCI were randomly divided into a treatment group（31 cases） and a control group（31 cases）. The control group was given conventional treatment

and the treatment group was given corresponding TCM syndrome differentiation treatment on the basis of the control group. Both groups were treated for 4 weeks. The efficacy of TCM syndrome

angina pectoris and electrocardiogram were compared between the 2 groups. The nitroglycerin use

blood lipids [triglyceride（TG）

high density lipoprotein cholesterol（HDL-C）

total cholesterol（TC）

low density lipoprotein cholesterin（LDL-C）]

high-sensitivity C-reactive protein（hs-CRP） and D-dimer（DD） levels were compared before and after treatment. Results In comparison of the efficacy of TCM symptom（87.10% in the treatment group and 58.06% in the control group）

angina pectoris（80.65% in the treatment group and 70.97% in the control group） and electrocardiogram（77.42% in the treatment group and 67.74% in the control group）

the treatment group was all superior to the control group（P<0.05）. After treatment

nitroglycerin usage

LDL-C

DD and hs-CRP of the 2 groups were significantly decreased than before（P<0.05）

and the level of above indexes of the treatment group was lower than those of the control group（P<0.05）. After treatment

HDL-C of the 2 groups was significantly increased than before（P<0.05）

and the level of HDL-C of the treatment group was higher than that of the control group（P<0.05）. Conclusion TCM syndrome differentiation treatment can significantly improve TCM symptoms

relieve angina pectoris

improve blood lipid levels

reduce hs-CRP and DD levels

and reduce the amount of nitroglycerin in patients with angina pectoris after PCI.

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