Objective To compare the clinical efficacy of different Chinese and western medicine anti-tuberculosis regimens in the treatment of cervical scrofula

and to analyze the correlation with use of surgical therapy and disease recurrence rate. Methods From October 1

2016 to July 1

2018

520 patients with cervical scrofula who received anti-tuberculosis treatment in Nanjing Hospital of Integrated Traditional Chinese and Western Medicine constituted a follow-up cohort. They entered the 3 queues including western medicine anti-tuberculosis treatment combined with traditional Chinese medicine（TCM） internal treatment group（control group Ⅰ）

western medicine anti-tuberculosis treatment combined with TCM external treatment group（control group Ⅱ） and western medicine anti-tuberculosis treatment combined with TCM comprehensive treatment group（observation group）. The TCM syndrome score and the maximum transverse diameter of lymphatic tuberculosis were compared after 4 weeks of treatment in each group of patients

and the selection of surgical treatment as well as recurrence were observed during the 1-year follow-up. Results A total of 449 cases were included in the analysis. After treatment

the TCM syndrome score and the maximum transverse diameter of lymph tuberculosis were reduced（P<0.05）. The improvement in the control group Ⅱ was superior to that in the control group Ⅰ（P<0.01）

and the improvement in the comprehensive treatment group was significantly higher than that of the control group Ⅱ（P<0.01）. According to the effective status after treatment（TCM syndrome score improving rate ≥70%） and surgical indications

139 patients chose anti-tuberculous non-surgical treatment and 381 patients chose surgical treatment. Among them

29 patients in the control group Ⅰ were included in non-surgical treatment. The control group Ⅱ included 38 patients with non-surgical treatment

and 72 patients received non-surgical treatment in the comprehensive treatment group. The lost follow-up rate was 8.85%（46/520） and the overall recurrence rate was 2.22%（10/449）. The recurrence rate of non-surgical patients was 2.24%（3/134）

and the recurrence rate of surgically treated patients was 2.22%（7/315）. There was no significant difference in the recurrence rate of surgically treated patients and non-surgically treated patients（P>0.05）. Conclusion The combination of TCM and western medicine against tuberculosis can effectively treat cervical scrofula

and the therapeutic effect of TCM combined with anti-tuberculosis western medicine is more significant. There is no specific correlation between surgical treatment and non-surgical treatment

but the comprehensive treatment of TCM combined with anti-tuberculosis western medicine can effectively reduce the incidence of surgery in patients with cervical scrofula.