The formation and development of atherosclerotic plaques are closely related to the local internal environment of the body. The plaque microenvironment includes the cellular components that make up the plaque itself and the factors secreted by them

as well as various pathological factors that exist in the microenvironment to promote plaque formation. In Chinese medicine

the balance of yin and yang is the basis for maintaining the normal life activities of the human body

and the formation of plaque is the result of the imbalance of yin and yang in its micro-environment. When the factors of various yin and yang properties in the micro-environment are over-converted

the unbalanced state is further aggravated

and finally the yin-yang rejection is caused

resulting in plaque rupture. Due to its multi-target regulation

traditional Chinese medicine has a significant effect in maintaining the balance of yin and yang in the body. Restoring the dynamic balance of yin and yang under disease state is the basic criterion for the treatment of atherosclerosis.