This study is to analyze the disease diagnosis and treatment system of Inner Canon of Yellow Emperor（《黄帝内经》） from the perspective of pathogenesis. In order to diagnose diseases

we should first examine the pathogenesis

which is at the core of the diagnosis and treatment of diseases in Inner Canon of Yellow Emperor. If we grasp the pathogenesis and control the nature of diseases and the key of treatment

in the face of the complex and changeable clinical situation

we can play a role in controlling the complexity. In addition

it also has important methodological enlightenment on the treatment of clinical trial mechanism

i.e. knowing its constancy and grasping its change is the guiding ideology of treatment; examining "the existence

nonexistence

deficiency and excess" is the thinking paradigm of clinical examination of pathogenesis; multidimensional synthesis and traversal is the implementation method of examination of pathogenesis. Finally

taking "heartache" as a typical case

the whole process of diagnosis and treatment of "heartache" was analyzed and presented based on pathogenesis in Inner Canon of Yellow Emperor.