ZHOU Zhongying′s experience in the treatment of fever in rheumatic and immune diseases is introduced. We summarizes the main pathogenesis of fever in rheumatic immune diseases is dampness

heat

turbidity

stasis and Shaoyang cardinal discord; the location of disease is mainly in half-exterior half-interior pattern; the nature of disease is mostly excessive heat

and common deficiency and excess are mixed. The clinical syndromes are mainly manifested by internal retention of damp-heat and cardinal discord. It is also often accompanied by syndromes such as external attack of pathogenic heat

mixed with blocked dampness and depression

or internal existence of pathogenic heat

or yin damage to qi loss. The treatment should be based on the basic principle of harmonization and clearance

playing the role of harmonizing the exterior and interior

yin and yang

ascending and descending. Clinical syndromes need to examine the mix

primary and secondary

and transformation of the pathogenesis

and treat it according to the syndrome; attention should be paid to latent pathogen

and the selection of drugs should be clearance and ventilation.