From childhood to adulthood

the development of the physiological state of "the spleen being often deficiency" to "the spleen being vigorous and free from pathogen in all seasons" is a self-organizing physiological process. The spleen viscera manifestation theory is a centerless（the spontaneous interaction of "qi and blood biochemistry" and "immune surveillance"）

multicenter（neuroendocrine and immune multiple systems） and one-center（the highest decision center: brain-gut axis） coordinated functional network

which is the integrated effect of biomechanics

biofilm

and mitochondria on material transport

energy conversion and signal transduction under the overall regulation of the neuroendocrine immune network dominated by the central nervous system/enteric nervous system. Different from the traditional system theory that implements top-down centralized control

the spleen-viscera manifestation system is a spontaneous bottom-up decentralized coordination

and it is also a combination of "gradual differentiation" and "gradual centralization".