Cancer related depression（CRD） refers to the significant and lasting depression of the patient due to tumor diagnosis

treatment and comorbidities. Tumor related mood disorder can be attributed to the category of "stagnation syndrome" in traditional Chinese medicine（TCM）. There are many visceras failure in patients with tumors

and the five visceras are not in charge of the functions

so emotions lose their functions. According to the different visceras that affect and qi

blood

yin and yang

different lesions of heart

liver

spleen

lung

and kidney deficiency are formed. In addition to supporting the vital qi and fighting against cancer

emotional intervention is particularly important for the treatment. The human body is an organic whole

and the five internal organs govern the five senses. Therefore

clinically

we should start from the five internal organs to regulate emotions and treat tumor related depression more effectively.