A comprehensive analysis on the clinical treatment data of early and full intervention of coronavirus disease 2019（COVID-19） with traditional Chinese medicine（TCM） from January to March 2020 was conducted. It is believed that the disease is mainly located in the lung

and it belongs to a dampness toxin pestilence. The change of the six exopathogens in different seasons and in different regions is the cause of disease occurrence

and the core pathogenesis is dampness

toxin

heat

phlegm

blood stasis and deficiency. The disease has the stage characteristics of the development of epidemic diseases such as pestilence toxin attacking the lungs

obstructing the lungs

closuring the lungs and disturbing the heart. The treatment should combine syndrome differentiation with disease differentiation

combining the severity and stage of the disease with TCM syndromes. Practice has proved that for patients of early mild and common types

ventilating the lungs and diffusing pathogen

dissipating dampness and detoxification should be applied. For the advanced severe cases

clearing heat and cooling blood

and removing blood stasis and dredging collaterals

can improve the curative rate of COVID-19

reduce the incidence of severe cases

and has a certain value in reducing the mortality rate.