Functional dyspepsia（FD） is located in the stomach and is related to the liver and spleen. Liver and spleen disorders are the key to its pathogenesis. Regulating the liver and spleen is the basic treatment method. Through combing and analyzing the clinical research and basic research literature of the treatment of FD by regulating the liver and regulating the spleen in the past two decades

it is proposed that the diagnosis

cause and pathogenesis

and syndrome type are clear

and the method of regulating the liver and the spleen is effective in treating FD. The treatment method can play important role in improving gastrointestinal motility

reducing visceral hypersensitivity

repairing the structure and function of the duodenum

and regulating brain-intestinal interaction.