WANG Min, QIAN Weiqiang, YUAN Weiling, et al. Correlation between Delayed Onset of Allergic Rhinitis and Meteorological Factors in Tianjin from 2007 to 2017: Based on the Theory of Hidden Pathogen[J]. Journal of Traditional Chinese Medicine2020, 61(23): 2063-2068.
WANG Min, QIAN Weiqiang, YUAN Weiling, et al. Correlation between Delayed Onset of Allergic Rhinitis and Meteorological Factors in Tianjin from 2007 to 2017: Based on the Theory of Hidden Pathogen[J]. Journal of Traditional Chinese Medicine2020, 61(23): 2063-2068.DOI: 10.13288/j.11-2166/r.2020.23.009.
Correlation between Delayed Onset of Allergic Rhinitis and Meteorological Factors in Tianjin from 2007 to 2017: Based on the Theory of Hidden Pathogen
Objective To explore the influence of meteorological factors on the delayed onset of allergic rhinitis. Methods The monthly data of allergic rhinitis cases and meteorological data in Tianjin from January 2007 to December 2017 were collected. Spearman correlation analysis and distributed lag nonlinear model(DLNM) provided by R 3.5.1 software and Splines software package were used to analyze the influence of meteorological factors on the delayed onset of allergic rhinitis. Results There were 2 peaks in the medical consultation rate of allergic rhinitis in Tianjin. The main peak occurred in August to September
the secondary peak occurred in April to May
and the medical consultation rate was the lowest in January to February. The number of monthly cases of allergic rhinitis was positively correlated with monthly relative humidity(r
s
=0.176)
monthly average temperature(r
s
=0.241)
monthly maximum temperature(r
s
=0.309)
and monthly sunshine hours(r
s
=0.55)(P
<
0.05); it was negatively correlated with monthly average wind speed(r
s
=0.229)(P
<
0.05). Allergic rhinitis delayed onset reached the first peak when the monthly average temperature was 25-30℃
monthly relative humidity was 35%-50%
and monthly sunshine hours was 300 h
and the lag time was respectively 1 month
0.5 month
and 0.5-1 month. The effect of onset reached the second peak while the monthly average wind speed was 1-1.5 m/s
2-2.5 m/s
and the lag time was 1 month and 2 months. The relationship between the hysteresis effect of various meteorological factors and the onset of allergic rhinitis
the hysteresis effect of high temperature 27.5℃ reached the highest at 1 month lag
and the relative risk(RR value) was 1.583(1.051-2.384)(P
<
0.05); The hysteresis effect of 45% humidity reached the highest at 0 month lag
and the RR value was 1.087(1.015-1.217)(P
<
0.05); the hysteresis effect of high sunshine hours of 256 h reached the highest at 1 month lag
and the RR value was 1.113(1.001-1.258)(P
<
0.05); the hysteresis effect of low wind speed of 1 m/s reached the highest when the lag was 0 months
the RR value was 1.062(1.003-1.213)(P
<
0.05). The hysteresis effect of the high wind speed of 2 m/s reached the highest when the lag was 2 months
and the RR value was 1.075(1.010-1.194)(P
<
0.05). Conclusion Monthly average temperature
monthly relative humidity
monthly sunshine hours and monthly average wind speed have an impact on the delayed onset of allergic rhinitis
especially the monthly average wind speed has the longest impact.