Objective To explore the clinical efficacy of integrated Chinese and western medicine in the treatment of coronavirus disease 2019（COVID-19） by retrospective analysis. Methods Clinical data of 64 COVID-19 patients in Raytheon Hill Hospital from February 16 to March 25

2020 was collected including general information

traditional Chinese medicine（TCM） syndrome

laboratory examination and treatment methods for retrospective study. According to different intervention methods

they were divided into an integrated Chinese and western medicine group（38 cases） and a western medicine group（26 cases）. The western medicine group was given antiviral

anti infective and auxiliary supporting drugs. The integrated treatment group was additionally given traditional Chinese medicine decoction and Chinese patent medicine according to syndrome differentiation and treatment. The time of clinical symptoms disappearance

TCM Syndrome Scale score

time to normal body temperature

lung CT improvement days

cases of common type patients turning to heavy or dying

adverse reactions

and laboratory indicators returning to normal when discharged were compared between groups. Results In the integrated treatment group

procalcitonin recovery rate was 100%

clinical symptoms disappear time of mild type（5.26±1.89） days

common type（9.67±1.96） days

severe type（12.12±1.43） days

recovery period（5.97± 2.01） days

time for lung CT image improvement（10.64±1.98） days

TCM syndrome scale score（6.84±3.78） points

time for body temperature return to normal（3.12±1.53） days. While in the western medicince group

procalcitonin recovery rate was 73.3%

clinical symptoms disappear time of mild type（7.18±2.15） days

common type（12.71±1.38） days

severe type（19.34±2.07） days

recovery period（7.83±1.52） days

time for lung CT image improvement（14.53±2.07） days

TCM syndrome scale score（13.32± 5.16） points

time for body temperature return to normal（5.26±1.72） days

the integrated treatment was supperior to the western medicine group significantly（P<0.05）; one case of adverse reaction occurred in each of the 2 groups. The number of cases of common type turing to severe（0/38 cases） in the integrated treatment group was significantly less than that in the western medicine group（3/26 cases

P<0.05）. Conclusion Integrated traditional Chinese and western medicine can significantly reduce the clinical symptoms

shorten the time of temperature normalization and the CT absorption time of lung in the treatment of COVID-19

the efficacy is better than that of western medicine alone.