Objective To explore the distribution law of phlegm and stasis（PSB） binding pattern in different stages of coronary heart disease（CHD）. Methods In a cross-section study design

11383 heathy people and CHD patients from 48 clinics in six regions of China were included and classified into healthy control group（HC）

low-risk group（LR）

metabolic syndrome（MS） group

CHD stable period（SP） group

acute coronary syndrome（ACS） group

perioperative period（PP） group

and CHD heart failure（HF） group according to the stages of CHD. Diagnosis Standards on CHD with PSB pattern was referred to when describing the distribution of PSB pattern

and the quantitative pattern score was calculated and analyzed. Results The proportion of phlegm-damp pattern and score（95% confidence interval） of HC group（27.7%

3.4-3.8 points）

LR group（43.3%

5.0-5.4 points）

MS group（65.1%

7.4-7.9 points）

SP group（75.1%

9.0-9.3 points）

ACS group（78.5%

9.3-10.0 points）

and HF group（78.6%

9.5-10.2 points） showed an increase trend. The proportion of blood stasis pattern and score increased from HC group（6.8%

1.0-1.3 points）

to LR group（16.0%

2.2-2.4 points）

MS group（21.9%

2.9-3.3 points）

SP group（63.5%

7.9-8.3 points）

HF group（69.2%

8.8-9.5 points）

and ACS group（78.9%

10.0-10.8 points）. The proportion of PSB pattern and score also increased from HC group（3.0%

4.5-5.0 points）

LR group（8.9%

7.2-7.7 points）

MS group（15.8%

10.3-11.0 points）

SP group（51.2%

16.9-17.5 points）

HF group（57.2%

18.3-19.5 points）

and ACS group（64.7%

19.4-20.6 points）. There were significant differences among six regions in pattern distribution and scores of phlegm-damp pattern

blood stasis pattern and PSB pattern（P<0.05）. The proportion and degree of PSB pattern were larger in North China and Northwest China than in other regions

while the proportion and degree of phlegm-damp pattern

blood stasis pattern

and PSB pattern were smallest in East China. The proportion and degree of three patterns in early stage of CHD including HC

LR

MS group were the largest in southern region including South China and Southwest China. Conclusion PSB pattern is the main pattern throughout all stages of CHD

and there are certain regional differences.