Objective To analyze the distribution of traditional Chinese medicine（TCM） syndromes and pathogenesis of children with Henoch-Schonlein purpura（HSP） in Henan province. Methods The clinical data including sex

age

place of residence

TCM diagnosis

western medicine diagnosis

TCM syndromes

and complications were retrospectively collected from children with HSP who were admitted to the hospital from January 2013 to December 2019

and the law of morbidity of HSP was summarized. Results A total of 14809 HSP chidlren were included

of which 8325（56.22%） were boys and 6484（43.68%） were girls at a ratio of 1.28 ∶1. The onset age ranged from 10 months to 18 years old with an average 107.16±40.93 months; preschool to early adolescence（4 to 15 years old） was the major onset period of HSP

and the incidence rate among school-age children（6 to 12 years old） was highest. Throughout the year

the highest incidence was in December

while the lowest incidence was in August; autumn and winter were the seasons of high incidence of disease. In terms of the geographical distribution of Henan province

areas such as Pingdingshan and Xuchang had relatively higher incidence of HSP

while areas adjacent to other provinces such as Sanmenxia

Xinyang

Anyang and Puyang had relatively lower incidence（the possibility of children seeking more convinient local medical service should be considered）. Among the HSP children of non-kidney damage type

bleeding due to blood-heat pattern was most commonly seen with 10307 cases

while among the HSP children of kidney damage type

blood heat with phlegm pattern was the most common TCM syndrome with 1716 cases. Conclusion The incidence of HSP in children may be associated with the climate

geographical area and children′s constitution. School-age children have highest incidence rate of HSP. Blood heat pattern is most commonly seen

and the main comorbidities are pulmonary diseases

especially common colds.