Chronic non-communicable diseases（chronic diseases） of unknown etiology or multiple causes are the majority of the modern diseases

which bring a heavy social and economic burden. Academician TONG Xiaolin advocates that the prevention and treatment of chronic diseases should return to the most basic and simplest state of the unity of heaven and humankind

and fundamentally adhere to the principle of "treating complexity with simplicity". Based on the four basic elements that nature has endowed human beings with

namely sunshine

water

air and nutrition

together with the natural laws of life being old and deficient

he outlines "ten states of chronic diseases"

which include cold state

hot state

dry state

wet state

constraint state

stasis state

barren state

congestion state

old state

and deficiency state. Based on clinical practice

the prevention and treatment strategy in relation to "ten states of chronic diseases" is summarized

that is

after the "state" is recognized and differentiated

corresponding state-modulating formula is prescribed

and symptom-target and indicator-target drugs are supplemented. This strategy combines the macro-level "state modulation" and micro-level "target treatment" in diagnosing and treating chronic diseases

which is a provoke-thinking exploration and can provide references for prevention and treatment of chronic diseases with traditional Chinese medicine in the context of modern medicine.