Objective To explore the electrical characteristics of twelve yuan-source points（原穴） and their correlation with diseases. Methods PubMed

Web of Science

CNKI

SinoMed

VIP and Wanfang Data were searched for papers involving electrical characteristics of Yuan-source points from their inception dates till October 10 th

2020. Database of included papers was established and data were extracted; the frequency of twelve Yuan-source points and electrical indicators were calculated based on bibliometric methods; the correlation between disease and electrical characteristics of Yuan-source points was assessed through network analysis method. Results A total of 86 papers were included. The top five Yuan-source points with high frequency were Chongyang（ST 42

n=57）

Taiyuan（LU 9

n=55）

Taichong（LV 3

n=53）

Taibai（SP 3

n=52）

and Taixi（KI 3

n=51）. The most frequent electric indicator was electric resistance（n=38）

followed by conductivity（n=16）

volt-ampere area（n=15） and inertial area（n=12）. There were 62 disease-related papers

of which digestive system diseases（16.92%）

circulatory system diseases（15.38%）

endocrine/nutrition and metabolic diseases（13.85%） were majorly investigated. Of the 14 papers providing information on relevance of internal organs disease and electronic characteristics of Yuan-source points

it was found that gastric and duodenal ulcers（n=12）

diabetic nephropathy（n=10）

and fatty liver（n=7） were the three largest out-degree diseases to Yuan-source points

and Chongyang（ST 42

n=8）

Daling（PC 7

n=6） and Taixi（KI 3

n=6） were the top three largest in-degree points. Conclusion Gastric and duodenal ulcers

diabetic nephropathy

and fatty liver can cause relatively more changes in the electrical characteristics of the Yuan-source points

of which Chongyang（ST 42）

Daling（PC 7） and Taixi（KI 3） are the mostly affected.