Discussion on Blood Vessels Regulating Method of Traditional Chinese Medicine for Graves′ Disease from Perspective of Angiogenesis Inhibition

MA Wenxin; LIU Jinmin; TANG Yang; ZHU Xiaoyun; XU Jing; LIU Ximing

doi:10.13288/j.11-2166/r.2021.14.007

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Discussion on Blood Vessels Regulating Method of Traditional Chinese Medicine for Graves′ Disease from Perspective of Angiogenesis Inhibition

更新时间：2021-11-10

- Discussion on Blood Vessels Regulating Method of Traditional Chinese Medicine for Graves′ Disease from Perspective of Angiogenesis Inhibition
- Journal of Traditional Chinese Medicine Vol. 62, Issue 14, Pages: 1224-1227(2021)
- 作者机构：
  
  1. 北京中医药大学研究生院
  2. 中国中医科学院广安门医院
  3. 北京中医药大学东方医院
  4. 北京中医药大学
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2021.14.007
  CLC： R259
- Published：2021
- 稿件说明：
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MA Wenxin, LIU Jinmin, TANG Yang, et al. Discussion on Blood Vessels Regulating Method of Traditional Chinese Medicine for Graves′ Disease from Perspective of Angiogenesis Inhibition[J]. Journal of Traditional Chinese Medicine2021, 62(14): 1224-1227.
DOI：

MA Wenxin, LIU Jinmin, TANG Yang, et al. Discussion on Blood Vessels Regulating Method of Traditional Chinese Medicine for Graves′ Disease from Perspective of Angiogenesis Inhibition[J]. Journal of Traditional Chinese Medicine2021, 62(14): 1224-1227. DOI： 10.13288/j.11-2166/r.2021.14.007.

摘要

从中医学视角来看

甲状腺多气多血

其生理功能有赖于血脉的重要作用。认为甲状腺血脉功能异常引起Graves病的发生

其主要病理因素为火、痰、瘀

而火、痰、瘀的产生与甲状腺血管新生密切相关。中医治疗Graves病的基本方法均与调血脉之法密切相关

药理研究亦表明

夏枯草、土贝母等常用于治疗Graves病的中药具有抑制血管新生的作用

因此抑制甲状腺血管新生可能是调血脉之法治疗Graves病的作用机制之一。

Abstract

Thyroid is considered to be full of qi and blood in traditional Chinese medicine（TCM）

and its physiological function is closely related to blood vessels. Abnormal function of thyroid blood vessels may lead to the occurrence of Graves′ disease（GD）. It is believed that the main pathological factors of Graves′ disease are fire

phlegm and stasis

the formulation of GD is closely related to thyroid angiogenesis. The basic TCM treatment methods for GD are all related to the regulation of blood vessels. Pharmacological studies have also shown that commonly used Chinese herbs for GD

such as Xiakucao（Spica Prunellae） and Tubeimu（Rhizoma Bolbostematis） Fritillaria vulgaris

have the effect of inhibiting angiogenesis. Therefore

the inhibition of thyroid angiogenesis may be one of the mechanism of blood vessels regulating method for GD.

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Related Author

MA Wenxin

ZHU Xiaoyun

WANG Chengna

XU Jing

LIU Ximing

TANG Yang

GU Yunhui

MOU Dandan

Related Institution

Dongzhimen Hospital，Beijing University of Chinese Medicine

Guang'anmen Hospital，China Academy of Chinese Medical Sciences

Beijing University of Chinese Medicine

Jiangsu Province Traditional Chinese Medicine Hospital

Graduate School of Nanjing University of Chinese Medicine

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