LI Yi,PANG Bo,HUA Baojin,et al.Discussion on Pathogenesis of Malignant Tumors based on Collateral Disease Theory of Traditional Chinese Medicine[J].Journal of Traditional Chinese Medicine,2022,63(15):1427-1430.
LI Yi,PANG Bo,HUA Baojin,et al.Discussion on Pathogenesis of Malignant Tumors based on Collateral Disease Theory of Traditional Chinese Medicine[J].Journal of Traditional Chinese Medicine,2022,63(15):1427-1430.DOI: 10.13288/j.11-2166/r.2022.15.006.
Discussion on Pathogenesis of Malignant Tumors based on Collateral Disease Theory of Traditional Chinese Medicine
This paper introduced the collateral disease theory of traditional Chinese medicine (TCM) into the tumor researches, and traced the development process of the collateral disease theory in literature. It is put forward that the basic pathogenesis of the formation, evolution, diffusion and metastasis of malignant tumors is “cancer toxin,collateral injury, healthy
qi
damage”, and the way of passing away is from
qi
to blood, and from blood to collaterals. The evolution process of the malignant tumors is the abnormal transformation of local biological mechanism under the influence of collateral hyperactivity and cancer toxin attacking the collaterals. Regarding the association between collateral disease theory and tumor pathogenesis, it is considered that the progress of tumor disease is related to latent cancer toxins in the collaterals gradually leading to collateral
qi
deficiency and stagnation, and longtime damage of collaterals and self-injury of healthy
qi
. The deficiency-excess complex and root deficiency-branch excess are the core pathogenesis of tumors.
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references
SUNG H , FERLAY J , SIEGEL RL , et al . Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J]. CA Cancer J Clin , 2021 , 71 ( 3 ): 209 - 249 .
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