This paper summarized GUO Zhiqiang's experience in treating ureaplasma urealyticum infection in the female reproductive tract. The main pathogenesis of this disease is damp-heat toxin accumulation and insect erosion of vulva， chronic disease with blood stasis， and deficiency of

zang

-

fu

organs （脏腑）， therefore it can be treated from four aspects including toxin， insect， stasis and deficiency. The general treatment principle is dispelling pathogen and supplementing deficiency， and the herbs should be flexibly used by differentiating the pathogenesis. If the excess pathogen is predominant， it is suggested to clear heat， resolve toxins and dispel dampness first， in combination with insects killing to relieve itching. When there is chronic disease with stasis， small amount of assistant herbs to invigorate blood and dissolve stasis should be used. For severe depletion of

zang

-

fu

organs， it is advised to care the healthy

qi

， timely adjust the attack and supplementation method by differentiating the healthy

qi

， pathogenic

qi

， deficiency and excess， and stop the treatment when there is effective trend of the symptoms. Additionally， the decocting method， the simultaneous treatment of the couple， and the lifestyle adjustment should be payed attention to.