This paper summarized LI Jiageng's experience in treating primary liver cancer based on six-channel and

zang

-

fu

（脏腑） pattern differentiation. It is believed that the occurrence and progression of liver cancer conforms to the characteristics of six-channel diseases， therefore， six-channel pattern differentiation is mainly used in clinical practice. As liver cancer is initially rooted in

shaoyang

（少阳） and

jueyin

（厥阴） channels， the treatment principle is unblocking the cardinal of

qi

movement， commonly with

Xiaochaihu Decoction

（小柴胡汤），

Sini Powder

（四逆散），

Shuanghe Decoction

（双合汤）， or

Biejiajian Pill

and

Wumei Pill

（鳖甲煎丸合乌梅丸）. If

taiyang

（太阳） channel is involved as well， it is recommended to release the exterior and dissipate pathogen， using

Chaihu Guizhi Decoction

（柴胡桂枝汤），

Xiaochaihu Decoction

with

Yinqiao Powder

or

modified Weirui Decoction

（小柴胡汤合银翘散或加减葳蕤汤）， or

Mahuang Shengma Decoction

（麻黄升麻汤）. If

yangming

（阳明） and

taiyin

（太阴） channel diseases are accompanied， the treatment should be supplementing deficiency and draining excess， commonly with

Wuwei Xiaodu Beverage

（五味消毒饮），

Dachaihu Decoction

（大柴胡汤），

Yinchenhao Decoction

（茵陈蒿汤），

Chaihu Liujunzi Decoction

（柴胡六君子汤）， or

Chaihu Guizhi Ganjiang Decoction

（柴胡桂枝干姜汤）. For the condition accompanied with

shaoyin

（少阴） diseases， it is advised to regulate and harmonize

yin

and

yang

， and the commonly used formulas were

Liuwei Dihuang Pill

with

Yiguan Decoction

（六味地黄丸合一贯煎）， or

Bawei Dihuang Pill

with

Yougui Pill

（八味地黄丸合右归丸）. Simultaneously，

zang

-

fu

pattern differentiation is used as supplement， where the deficiency and excess of

zang

-

fu

organs is judged by tongue and pulse manifestations. The treatment principle is to curb a surplus and supplement deficiency， thereby cutting off the transmission and change of the

zang

-

fu

organs.