Constructing the State-Target Differentiation and Treatment System of Primary Membranous Nephropathy based on the Theory of Zang-fu (脏腑) Organs Wind-damp
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Constructing the State-Target Differentiation and Treatment System of Primary Membranous Nephropathy based on the Theory of Zang-fu (脏腑) Organs Wind-damp
Journal of Traditional Chinese MedicineVol. 64, Issue 8, Pages: 774-778(2023)
ZHAO Qihan,DAI Haoran,JIANG Hanxue,et al.Constructing the State-Target Differentiation and Treatment System of Primary Membranous Nephropathy based on the Theory of Zang-fu (脏腑) Organs Wind-damp[J].Journal of Traditional Chinese Medicine,2023,64(08):774-778.
ZHAO Qihan,DAI Haoran,JIANG Hanxue,et al.Constructing the State-Target Differentiation and Treatment System of Primary Membranous Nephropathy based on the Theory of Zang-fu (脏腑) Organs Wind-damp[J].Journal of Traditional Chinese Medicine,2023,64(08):774-778.DOI: 10.13288/j.11-2166/r.2023.08.005.
Constructing the State-Target Differentiation and Treatment System of Primary Membranous Nephropathy based on the Theory of Zang-fu (脏腑) Organs Wind-damp
Primary membranous nephropathy (PMN) is an autoimmune glomerular disease, which has become the main pathological condition of nephrotic syndrome in adults, and belongs to “edema” in traditional Chinese medicine. Based on the theories of
zang
-
fu
(脏腑) organs wind-damp, and state differentiation and target treatment, it is proposed that PMN can be divided into four stages according to the progression of the pathological mechanism, that is deficiency, latency, change, and depletion, and the six states of the clinical manifestations include deficiency, cold, damp, stasis, accumulation, and retention.
Mahuang Fuzi Decoction and Shenzhuo Decoction
(麻黄附子汤合肾着汤) is the main prescription targeting the disease. Aiming at the three contained targets of immunity, pathology, and indicators, the prescription should be flexibly modified based on the six states, and the principle of warming yang and removing accumulation, releasing the exterior and dissipating cold should be adhered to, in order to construct a state-target differentiation and treatment system for PMN.
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