YAO Naili's Experience in Differentiating and Treating Primary Sclerosing Cholangitis by Stages

WANG Li; ZHANG Runshun; LYU Wenliang

doi:10.13288/j.11-2166/r.2023.10.003

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YAO Naili's Experience in Differentiating and Treating Primary Sclerosing Cholangitis by Stages

更新时间：2023-05-13

- YAO Naili's Experience in Differentiating and Treating Primary Sclerosing Cholangitis by Stages
- Journal of Traditional Chinese Medicine Vol. 64, Issue 10, Pages: 983-987(2023)
- 作者机构：
  
  1.中国中医科学院广安门医院，北京市西城区北线阁5号，100053
  2.北京中医药大学研究生院
  3.中国中医科学院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2023.10.003
  CLC：
- Received：10 June 2022，
  
  Revised：2022-12-08，
  
  Published：17 May 2023
- 稿件说明：
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王丽,张润顺,吕文良等.姚乃礼分期辨治原发性硬化性胆管炎经验[J].中医杂志,2023,64(10):983-987.

WANG Li,ZHANG Runshun,LYU Wenliang.YAO Naili's Experience in Differentiating and Treating Primary Sclerosing Cholangitis by Stages[J].Journal of Traditional Chinese Medicine,2023,64(10):983-987.
王丽,张润顺,吕文良等.姚乃礼分期辨治原发性硬化性胆管炎经验[J].中医杂志,2023,64(10):983-987. DOI： 10.13288/j.11-2166/r.2023.10.003.

WANG Li,ZHANG Runshun,LYU Wenliang.YAO Naili's Experience in Differentiating and Treating Primary Sclerosing Cholangitis by Stages[J].Journal of Traditional Chinese Medicine,2023,64(10):983-987. DOI： 10.13288/j.11-2166/r.2023.10.003.

摘要

总结姚乃礼教授治疗原发性硬化性胆管炎的临床经验。认为本病病机特点为正虚邪盛，脾虚不运是贯穿于本病发生发展的根本原因，肝胆失于疏利是重要因素。临床应根据不同病程阶段进行辨证分析，早期证型多为肝脾不和、湿热蕴结、血虚风燥，迁延期证型多为肝郁脾虚、血瘀成积、脾虚湿滞，后期证型多为肝肾阴虚、阳虚水泛。临证时善用黄芪健脾土，滋肾水以调肝，同时整体调治顾兼病，临床疗效显著。

Abstract

This paper summarized the clinical experience of professor YAO Naili in the treatment of primary sclerosing cholangitis （PSC）. The pathogenesis of this disease is characterized by healthy

deficiency and pathogen excess， with spleen deficiency failing to transport as the root cause， and the liver and gallbladder loss of soothing and draining as an important factor. Clinical treatment should be performed based on syndrome differentiation at different stages of the disease. At early stage， liver-spleen disharmony syndrome， damp-heat accumulation syndrome， and blood deficiency and wind-dryness syndrome are common. At the protracted stage， liver constraint and spleen deficiency syndrome， blood stasis accumulation syndrome， and spleen deficiency and dampness stagnation syndrome are the most frequent types. At the late stage， liver-kidney

yin

deficiency syndrome and edema due to yang deficiency syndrome are commonly seen. In clinical practice， Huangqi （

Radix Astragali

） is usually used to fortify spleen earth and enrich kidney water thereby regulating the liver. At the same time， the combined diseases are also treated with the concept of holism， obtaining remarkable clinical effect.

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references

TRIVEDI PJ ， HIRSCHFIELD GM . Recent advances in clinical practice： epidemiology of autoimmune liver diseases ［J］. Gut ， 2021 ， 70 （ 10 ）： 1989 - 2003 .

郭长存，时永全，尚玉龙，等 . 原发性硬化性胆管炎诊断及治疗指南（2021）［J］. 临床肝胆病杂志， 2022 ， 38 （ 1 ）： 50 - 61 .

古杰，蒋文涛，李江，等 . 肝移植治疗终末期自身免疫性肝病的临床分析［J］. 中华危重病急救医学， 2019 ， 31 （ 11 ）： 1401 - 1405 .

中华医学会肝病学分会 . 原发性硬化性胆管炎诊断及治疗指南（2021）［J］. 中华肝脏病杂志， 2022 ， 30 （ 2 ）： 169 - 189 .

王璐，韩英 . 原发性硬化性胆管炎诊治进展［J］. 中国医学前沿杂志（电子版）， 2020 ， 12 （ 2 ）： 7 - 12 .

浦仕彪，王伽伯，王睿林，等 . 中医和中西医结合治疗自身免疫性肝炎的优势与挑战［J］. 中国实验方剂学杂志， 2016 ， 22 （ 23 ）： 197 - 202 .

李时珍 . 本草纲目［M］. 柳长华，柳璇，点校.北京：中国医药科技出版社， 2011 ： 94 .

张家礼 . 普通高等教育“十五”国家级规划教材·金匮要略［M］. 北京：中国中医药出版社， 2004 ： 120 - 126 .

王琦，季书，尚立芝，等 . 柴胡疏肝散对免疫损伤性肝纤维化的防治作用［J］. 中国实验方剂学杂志， 2014 ， 20 （ 24 ）： 159 - 163 .

柴智，杜珊，樊慧杰，等 . 逍遥散及其加减治疗肝病的临床应用及现代研究进展［J］. 中华中医药杂志， 2017 ， 32 （ 8 ）： 3631 - 3634 .

潘秋霞 . 肝郁脾虚证大鼠肝脏能量代谢紊乱的机制及逍遥散的调节作用［D］. 北京：北京中医药大学， 2018 .

王忠利，王洪新 . 黄芪多糖对免疫性肝损伤大鼠的保护作用研究［J］. 中药药理与临床， 2013 ， 29 （ 2 ）： 77 - 80 .

李天一，吴国琳，汪丽佩 . 黄芪多糖对免疫性肝损伤小鼠协同刺激分子的影响研究［J］. 中华中医药学刊， 2014 ， 32 （ 3 ）： 529 - 531 .

刘思美，赵鹏，张婷婷，等 . 地黄硒多糖的合成、表征及免疫活性分析［J］. 中国中药杂志， 2022 ， 47 （ 11 ）： 2938 - 2946 .

车招娣，周正群，肖佳 . 宁夏枸杞子治疗肝脏疾病的作用机制［J］. 科学通报， 2022 ， 67 （ Z1 ）： 351 - 363 .

刘淑萍，张新渐，王洪云，等 . 乌头属中药多糖研究进展［J］. 中国药业， 2019 ， 28 （ 3 ）： 1 - 6 .

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