During the long struggle with the epidemics， traditional Chinese medicine （TCM） has gradually formed a complete theoretical system for the prevention and treatment of recurrence and symptoms after recovery. A series of symptoms during the recovery period of the epidemic was referred as “post-epidemic syndromes”. This paper compiled the literature of physicians in the past generations， and sorted out the understanding of the theory of “post-epidemic syndromes” in each period according to the main line of time. In the pre-Qin period， the theory of “post-epidemic syndromes” is in its infancy， when the etiology， pathogenesis， and treatment were preliminarily expounded. In the Han and Tang dynasties， the theory was differentiated into two categories， namely， recurrent symptoms and symptoms after recovery. In the Song， Jin and Yuan dynasties， the theory of epidemic diseases was enriched and developed. During the Ming and Qing dynasties， a complete theory of “post-epidemic syndromes” and the syndrome differentiation and treatment system has been formed through summary and innovation in terms of causes， syndrome， pulse and treatment. On this thoery basis and the experience of the prevention and control of the COVID-19， the theoretical system of “post-epidemic syndromes” was initially constructed in order to provide clinical guidance for the prevention and treatment of epidemic disease in the recovery period with TCM.